Which type of anti-hypertensive medication is used when ACE inhibitors are inappropriate?

When considering antihypertensive medications to use when ACE inhibitors are inappropriate, Angiotensin Receptor Blockers (ARBs) are a suitable alternative. ARBs work by blocking the action of angiotensin II at its receptor, which helps to lower blood pressure without the side effects associated with ACE inhibitors, such as cough or angioedema. This is particularly important in patients who may experience these adverse reactions to ACE inhibitors but still require effective management of hypertension.

ARBs are beneficial as they provide similar protective effects on the kidneys and heart, making them a good choice in managing hypertension, especially in patients with conditions like diabetes or heart failure. This makes them a preferred option when ACE inhibitors cannot be used due to intolerance or other contraindications.

While beta blockers, calcium channel blockers, and vasodilators are also effective in managing hypertension, they work through different mechanisms and may not offer the same renal protective benefits as ARBs. Thus, in scenarios where ACE inhibitors are deemed inappropriate, ARBs are often the first choice for continuing the management of hypertension.