Which of the following is a typical side effect of SIRT?

The side effects associated with Selective Internal Radiation Therapy (SIRT) are well-documented and occur due to the procedure's impact on the liver and surrounding tissues. Nausea and anorexia are particularly common because SIRT involves delivering radioactive microspheres directly to the liver tumor. This concentrated radiation can irritate the gastrointestinal tract, leading to symptoms like nausea and a loss of appetite (anorexia).

Additionally, the liver plays a significant role in metabolism and can be affected by the treatment, further contributing to these symptoms. Fatigue can also occur, but it is not as direct or immediate a symptom as nausea and anorexia following SIRT. Headache and rash, although they can occur in some patients post-treatment, are not typically emphasized in the context of SIRT side effects. Engaging with patients about potential side effects prior to the procedure includes a more focused discussion on nausea and appetite changes, making this the most representative answer for typical side effects of SIRT.