Which leads are affected in lateral STEMI?

In the context of lateral ST-Elevation Myocardial Infarction (STEMI), the leads that are indicative of such an event are specifically those that monitor the lateral wall of the left ventricle. The correct choice highlights leads I, aVL, V5, and V6, which collectively provide insight into the electrical activity of the heart as it pertains to the lateral wall.

Lead I views the lateral aspect of the heart, primarily reflecting activity from the left lateral wall. Similarly, lead aVL also observes the lateral wall but offers a slightly elevated perspective. V5 and V6 are positioned laterally on the chest and are crucial in detecting changes in the heart's electrical activity during a lateral STEMI.

When there's an elevation in the ST-segment in these leads, it indicates that there is an obstruction or significant ischemia affecting the blood supply to the lateral wall, typically due to occlusion of the left circumflex artery or a branch thereof. This combination of leads provides a focused view to diagnose lateral STEMI effectively.

The other options either include leads that would typically not indicate a lateral STEMI or do not reflect the appropriate combination needed to confirm such a diagnosis. In particular, leads like V1 and V2 are positioned