What mechanism does a Trellis device utilize to macerate a clot?

The Trellis device uses an oscillating nitinol wire to effectively macerate a clot. Nitinol is a nickel-titanium alloy known for its unique properties, including shape memory and superelasticity. When the nitinol wire within the Trellis device oscillates, it generates mechanical agitation that disrupts the structure of the clot. This mechanical action helps to emulsify the clot, breaking it into smaller particles that can be more easily removed from the vascular system.

This mechanism is particularly effective because it allows the device to target and treat thrombus in a way that promotes rapid dissolution without causing significant damage to surrounding healthy tissue. The use of oscillating nitinol wire represents a blend of biochemical and mechanical approaches to thrombus management, maximizing the efficacy of the procedure while minimizing risks.

Understanding the specific function of the oscillating nitinol wire reveals how the Trellis device uniquely contributes to interventional radiology practices focused on clot management, particularly in conditions like deep vein thrombosis or pulmonary embolism, where clot fragmentation is critical for restoring normal blood flow.