In TACE, where is chemotherapy injected?

In transarterial chemoperfusion, commonly known as TACE (Transarterial Chemoembolization), chemotherapy is specifically injected into the arteries that supply blood to the tumor lesions. This targeted approach allows for a higher concentration of the chemotherapy agent to be delivered directly to the cancerous tissue, while minimizing the systemic exposure and potential side effects compared to intravenous administration.

By focusing on the arteries that feed the tumor, TACE not only provides localized treatment but also often includes agents that embolize (block) the blood supply to the tumor, further enhancing the efficacy of the chemotherapy. This method distinguishes TACE from other treatments that might administer drugs through systemic routes or localize them directly within the tumor mass, which are not the standard protocols in TACE.